The IGS Annotation Engine provides free automated annotation of prokaryotic sequences using the IGS prokaryotic annotation pipeline. In addition, the manual annotation tool Manatee is available for viewing and curating the data.
To submit sequence to the Annotation Engine, simply send the sequence in a FASTA formated file. Please don't send zip files as they are blocked by our university mail system but other forms of compression are fine. Please let us know if the genomes are complete or in a draft state. If they are draft genomes there are two options for doing the annotation: 1. on the contigs; 2. on a pseudomolecule (contigs linked together into one long sequence with a spacer between each contig that introduces starts and stops in all 6 frames). We can generate the psueudomolecules for you if you wish us to. Also, if there is a close relative of your strain that has its sequence completed we can use that to order your contigs. If not, we can order the contigs longest to shortest. Please contact us if you are not sure which option (contigs/pseudomolecule) is best for you and we can provide some help in making the decision.
If you have a genome to submit, please contact us for more information.
We ask that anyone using the IGS Annotation Engine for their work include that information in the Materials and Methods section and to acknowledge us in the Acknowledgements section. Thank You.
IMPORTANT NOTICE TO ANNOTATION ENGINE USERS: We are pleased to announce that what was one automated annotation service has now become two. This will allow us to serve twice as many users. What was previously the TIGR/JCVI Annotation Engine service has now branched into two new services: one offered by the J. Craig Venter Institute (JCVI), called "The JCVI Annotation Service", the other offered by the Institute for Genome Sciences (IGS) at the University of Maryland, School of Medicine called "The IGS Annotation Engine". The managers of both services are in active collaboration with one another. We encourage you to explore the web sites of the two services to learn more about the two great choices now available.